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Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression

BACKGROUND: Glutathione S-transferase mu 3 (GSTM3) has been proven to be downregulated in renal cell carcinoma (RCC). We aimed to characterise the role of GSTM3 and its genetic predisposition on the occurrence and postoperative prognosis of RCC. METHODS: The effect of GSTM3 on RCC aggressiveness was...

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Detalles Bibliográficos
Autores principales:	Tan, X, Wang, Y, Han, Y, Chang, W, Su, T, Hou, J, Xu, D, Yu, Y, Ma, W, Thompson, T C, Cao, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859948/ https://www.ncbi.nlm.nih.gov/pubmed/24157827 http://dx.doi.org/10.1038/bjc.2013.669

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