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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes

Mammalian oocyte maturation is distinguished by highly asymmetric meiotic divisions during which a haploid female gamete is produced and almost all the cytoplasm is maintained in the egg for embryo development. Actin-dependent meiosis I spindle positioning to the cortex induces the formation of a po...

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Detalles Bibliográficos
Autores principales: Wang, Zhen-Bo, Jiang, Zong-Zhe, Zhang, Qing-Hua, Hu, Meng-Wen, Huang, Lin, Ou, Xiang-Hong, Guo, Lei, Ouyang, Ying-Chun, Hou, Yi, Brakebusch, Cord, Schatten, Heide, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861080/
https://www.ncbi.nlm.nih.gov/pubmed/24131996
http://dx.doi.org/10.1091/mbc.E13-03-0123