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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes
Mammalian oocyte maturation is distinguished by highly asymmetric meiotic divisions during which a haploid female gamete is produced and almost all the cytoplasm is maintained in the egg for embryo development. Actin-dependent meiosis I spindle positioning to the cortex induces the formation of a po...
Autores principales: | Wang, Zhen-Bo, Jiang, Zong-Zhe, Zhang, Qing-Hua, Hu, Meng-Wen, Huang, Lin, Ou, Xiang-Hong, Guo, Lei, Ouyang, Ying-Chun, Hou, Yi, Brakebusch, Cord, Schatten, Heide, Sun, Qing-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861080/ https://www.ncbi.nlm.nih.gov/pubmed/24131996 http://dx.doi.org/10.1091/mbc.E13-03-0123 |
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