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A Small RNA Encoded in the Rv2660c Locus of Mycobacterium tuberculosis Is Induced during Starvation and Infection

Enhanced transcription of the Rv2660c locus in response to starvation of Mycobacterium tuberculosis H37Rv encouraged addition of the predicted Rv2660c protein to an improved vaccine formulation. Using strand-specific RNA sequencing, we show that the up-regulated transcript is in fact a small RNA enc...

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Detalles Bibliográficos
Autores principales: Houghton, Joanna, Cortes, Teresa, Schubert, Olga, Rose, Graham, Rodgers, Angela, De Ste Croix, Megan, Aebersold, Rudolf, Young, Douglas B., Arnvig, Kristine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861185/
https://www.ncbi.nlm.nih.gov/pubmed/24348997
http://dx.doi.org/10.1371/journal.pone.0080047