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ESAT-6 (EsxA) and TB10.4 (EsxH) Based Vaccines for Pre- and Post-Exposure Tuberculosis Vaccination

The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of highly immunogenic proteins of key importance for bacterial survival and growth. The two prototypic proteins, ESAT-6 (EsxA from ESX-1) and TB10.4 (EsxH from ESX-3) share a lot of characteristics regarding genome org...

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Detalles Bibliográficos
Autores principales: Hoang, Truc, Aagaard, Claus, Dietrich, Jes, Cassidy, Joseph P., Dolganov, Gregory, Schoolnik, Gary K., Lundberg, Carina Vingsbo, Agger, Else Marie, Andersen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861245/
https://www.ncbi.nlm.nih.gov/pubmed/24349004
http://dx.doi.org/10.1371/journal.pone.0080579