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Human CD8(+) T Cells from TB Pleurisy Respond to Four Immunodominant Epitopes in Mtb CFP10 Restricted by HLA-B Alleles

CD8(+) T cells are essential for host defense to Mycobacterium tuberculosis (Mtb) infection and identification of CD8(+) T cell epitopes from Mtb is of importance for the development of effective peptide-based diagnostics and vaccines. We previously demonstrated that the secreted 10-KDa culture filt...

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Detalles Bibliográficos
Autores principales: Li, Li, Yang, Binyan, Yu, Sifei, Zhang, Xianlan, Lao, Suihua, Wu, Changyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861325/
https://www.ncbi.nlm.nih.gov/pubmed/24349220
http://dx.doi.org/10.1371/journal.pone.0082196