Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4

BACKGROUND: It has been hypothesized that persistent hepatitis C virus (HCV) infection is mediated in part by viral proteins that abrogate the host immune response, including the complement system, but the precise mechanisms are not well understood. We investigated whether HCV proteins are involved...

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Detalles Bibliográficos
Autores principales: Mawatari, Seiichi, Uto, Hirofumi, Ido, Akio, Nakashima, Kenji, Suzuki, Tetsuro, Kanmura, Shuji, Kumagai, Kotaro, Oda, Kohei, Tabu, Kazuaki, Tamai, Tsutomu, Moriuchi, Akihiro, Oketani, Makoto, Shimada, Yuko, Sudoh, Masayuki, Shoji, Ikuo, Tsubouchi, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861371/
https://www.ncbi.nlm.nih.gov/pubmed/24349192
http://dx.doi.org/10.1371/journal.pone.0082094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861371/
https://www.ncbi.nlm.nih.gov/pubmed/24349192
http://dx.doi.org/10.1371/journal.pone.0082094

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