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Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4
BACKGROUND: It has been hypothesized that persistent hepatitis C virus (HCV) infection is mediated in part by viral proteins that abrogate the host immune response, including the complement system, but the precise mechanisms are not well understood. We investigated whether HCV proteins are involved...
Autores principales: | Mawatari, Seiichi, Uto, Hirofumi, Ido, Akio, Nakashima, Kenji, Suzuki, Tetsuro, Kanmura, Shuji, Kumagai, Kotaro, Oda, Kohei, Tabu, Kazuaki, Tamai, Tsutomu, Moriuchi, Akihiro, Oketani, Makoto, Shimada, Yuko, Sudoh, Masayuki, Shoji, Ikuo, Tsubouchi, Hirohito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861371/ https://www.ncbi.nlm.nih.gov/pubmed/24349192 http://dx.doi.org/10.1371/journal.pone.0082094 |
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