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Molecular Basis of Drug Resistance: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Anaplastic Lymphoma Kinase Inhibitors
Over the past decade, several kinase inhibitors have been approved based on their clinical benefit in cancer patients. Unfortunately, in many cases, patients develop resistance to these agents via secondary mutations and alternative mechanisms. To date, several major mechanisms of acquired resistanc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Academy of Tuberculosis and Respiratory Diseases
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861374/ https://www.ncbi.nlm.nih.gov/pubmed/24348666 http://dx.doi.org/10.4046/trd.2013.75.5.188 |