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Secreted hCLCA1 Is a Signaling Molecule That Activates Airway Macrophages

The CLCA gene family produces both secreted and membrane-associated proteins that modulate ion-channel function, drive mucus production and have a poorly understood pleiotropic effect on airway inflammation. The primary up-regulated human CLCA ortholog in airway inflammation is hCLCA1. Here we show...

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Detalles Bibliográficos
Autores principales:	Ching, John C. H., Lobanova, Liubov, Loewen, Matthew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861482/ https://www.ncbi.nlm.nih.gov/pubmed/24349445 http://dx.doi.org/10.1371/journal.pone.0083130

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