KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan

Natural killer cell responses play a crucial role in virus clearance by the innate immune system. Although the killer immunoglobulin-like receptor (KIR) in combination with its cognate human leukocyte antigen (HLA) ligand, especially KIR2DL3-HLA-C1, is associated with both treatment-induced and spon...

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Detalles Bibliográficos
Autores principales: Nozawa, Yuichi, Umemura, Takeji, Joshita, Satoru, Katsuyama, Yoshihiko, Shibata, Soichiro, Kimura, Takefumi, Morita, Susumu, Komatsu, Michiharu, Matsumoto, Akihiro, Tanaka, Eiji, Ota, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861489/
https://www.ncbi.nlm.nih.gov/pubmed/24349500
http://dx.doi.org/10.1371/journal.pone.0083381

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