Enterohemorrhagic Escherichia coli Hemolysin Employs Outer Membrane Vesicles to Target Mitochondria and Cause Endothelial and Epithelial Apoptosis

Enterohemorrhagic Escherichia coli (EHEC) strains cause diarrhea and hemolytic uremic syndrome resulting from toxin-mediated microvascular endothelial injury. EHEC hemolysin (EHEC-Hly), a member of the RTX (repeats-in-toxin) family, is an EHEC virulence factor of increasingly recognized importance....

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Detalles Bibliográficos
Autores principales: Bielaszewska, Martina, Rüter, Christian, Kunsmann, Lisa, Greune, Lilo, Bauwens, Andreas, Zhang, Wenlan, Kuczius, Thorsten, Kim, Kwang Sik, Mellmann, Alexander, Schmidt, M. Alexander, Karch, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861543/
https://www.ncbi.nlm.nih.gov/pubmed/24348251
http://dx.doi.org/10.1371/journal.ppat.1003797

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