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Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production

The present study investigated the role of extracellular signal-regulated kinase (ERK) activation in the migratory phenotype of human U2OS osteosarcoma (OS) cells in a collagen matrix. The activation of ERK was inhibited by PD98059, a specific inhibitor of ERK kinase. Additionally, no significant di...

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Detalles Bibliográficos
Autores principales:	POUDEL, BARUN, KIM, DO-KUK, KI, HYEON-HUI, KWON, YOUNG-BAE, LEE, YOUNG-MI, KIM, DAE-KI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861606/ https://www.ncbi.nlm.nih.gov/pubmed/24348851 http://dx.doi.org/10.3892/ol.2013.1655

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