Cargando…

Defect of Mitotic Vimentin Phosphorylation Causes Microophthalmia and Cataract via Aneuploidy and Senescence in Lens Epithelial Cells

Vimentin, a type III intermediate filament (IF) protein, is phosphorylated predominantly in mitosis. The expression of a phosphorylation-compromised vimentin mutant in T24 cultured cells leads to cytokinetic failure, resulting in binucleation (multinucleation). The physiological significance of inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsuyama, Makoto, Tanaka, Hiroki, Inoko, Akihito, Goto, Hidemasa, Yonemura, Shigenobu, Kobori, Kyoko, Hayashi, Yuko, Kondo, Eisaku, Itohara, Shigeyoshi, Izawa, Ichiro, Inagaki, Masaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861614/ https://www.ncbi.nlm.nih.gov/pubmed/24142690 http://dx.doi.org/10.1074/jbc.M113.514737

Ejemplares similares

Outcomes of cataract surgery in Microophthalmia
por: Majid, Saima, et al.
Publicado: (2018)

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice
por: Tanaka, Hiroki, et al.
Publicado: (2015)

Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells
por: Inoko, Akihito, et al.
Publicado: (2012)

Cell cycle progression by the repression of primary cilia formation in proliferating cells
por: Goto, Hidemasa, et al.
Publicado: (2013)

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway
por: Inaba, Hironori, et al.
Publicado: (2016)

The keratin-binding protein Albatross regulates polarization of epithelial cells
por: Sugimoto, Masahiko, et al.
Publicado: (2008)

Trans-Sellar Trans-Sphenoidal Herniation of Third Ventricle with Cleft Palate and Microophthalmia: Report of a Case and Review of Literature
por: Bhaisora, Kamlesh Singh, et al.
Publicado: (2018)

Detection of mitotic and meiotic aneuploidy in the yeast Saccharomyces cerevisiae.
por: Parry, J M, et al.
Publicado: (1979)

Mitotic errors, aneuploidy and micronuclei in Hodgkin lymphoma pathogenesis
por: Krem, Maxwell M., et al.
Publicado: (2013)

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis
por: Yamaguchi, Tomoya, et al.
Publicado: (2005)

Current topics of functional links between primary cilia and cell cycle
por: Izawa, Ichiro, et al.
Publicado: (2015)

Different cell fates after mitotic slippage: From aneuploidy to polyploidy
por: Ohashi, Akihiro
Publicado: (2015)

USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
por: Campos-Iglesias, Diana, et al.
Publicado: (2023)

Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit
por: Nakajima, Hiroyuki, et al.
Publicado: (2008)

Phosphorylation of keratin and vimentin polypeptides in normal and transformed mitotic human epithelial amnion cells: behavior of keratin and vimentin filaments during mitosis
Publicado: (1983)

An Automated T-maze Based Apparatus and Protocol for Analyzing Delay- and Effort-based Decision Making in Free Moving Rodents
por: Zhang, Qi, et al.
Publicado: (2018)

Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast
por: Blank, Heidi M., et al.
Publicado: (2015)

Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development
por: McCoy, Rajiv C., et al.
Publicado: (2015)

Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos
por: McCoy, Rajiv C., et al.
Publicado: (2023)

The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy
por: Asteriti, Italia Anna, et al.
Publicado: (2014)

DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development
por: Ichijima, Yosuke, et al.
Publicado: (2010)

Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells
por: Cimini, Daniela, et al.
Publicado: (2001)

DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy
por: Costa, Giuseppe, et al.
Publicado: (2016)

BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer
por: Weaver, Robbyn L, et al.
Publicado: (2016)

Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations
por: Caneus, Julbert, et al.
Publicado: (2018)

The hippocampus encodes delay and value information during delay-discounting decision making
por: Masuda, Akira, et al.
Publicado: (2020)

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy
por: Sudo, Haruka, et al.
Publicado: (2016)

Vimentin and Anti Vimentin Antibodies in Chagas' Disease
por: Nascimento, Marilda Savoia, et al.
Publicado: (2018)

Phosphorylation of vimentin in mitotically selected cells. In vitro cyclic AMP-independent kinase and calcium-stimulated phosphatase activities
Publicado: (1989)

SHG-specificity of cellular Rootletin filaments enables naïve imaging with universal conservation
por: Akiyama, Toshihiro, et al.
Publicado: (2017)

Vimentin organization modulates the formation of lamellipodia
por: Helfand, Brian T., et al.
Publicado: (2011)

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
por: Weaver, Beth A.A., et al.
Publicado: (2003)

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence
por: Macedo, Joana Catarina, et al.
Publicado: (2018)

Aurora B prevents aneuploidy via MAD2 during the first mitotic cleavage in oxidatively damaged embryos
por: Li, Jiena, et al.
Publicado: (2019)

Differential Sensitivity of Epithelial Cells to Extracellular Matrix in Polarity Establishment
por: Yonemura, Shigenobu
Publicado: (2014)

Bicyclic Chalcones as Mitotic Inhibitors for Overcoming Androgen Receptor-Independent and Multidrug-Resistant Prostate Cancer
por: Saito, Yohei, et al.
Publicado: (2021)

Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes
por: de Pablo, Yolanda, et al.
Publicado: (2019)

PI 3-kinase-dependent phosphorylation of Plk1–Ser99 promotes association with 14-3-3γ and is required for metaphase–anaphase transition
por: Kasahara, Kousuke, et al.
Publicado: (2013)

Mitotic Defects Lead to Pervasive Aneuploidy and Accompany Loss of RB1 Activity in Mouse Lmna(Dhe) Dermal Fibroblasts
por: Pratt, C. Herbert, et al.
Publicado: (2011)

Genetic dissection of medial habenula–interpeduncular nucleus pathway function in mice
por: Kobayashi, Yuki, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b8m0h1qk5r6rkd8git4hvrh3vi