Cargando…

Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome

The peptide repertoire (peptidome) associated with MHC class II molecules (MHCIIs) is influenced by the polymorphic nature of the peptide binding groove but also by cell-intrinsic factors. The invariant chain (Ii) chaperones MHCIIs, affecting their folding and trafficking. Recent discoveries relatin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fortin, Jean-Simon, Cloutier, Maryse, Thibodeau, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861868/ https://www.ncbi.nlm.nih.gov/pubmed/24379812 http://dx.doi.org/10.3389/fimmu.2013.00443

Ejemplares similares

GILT: Shaping the MHC Class II-Restricted Peptidome and CD4(+) T Cell-Mediated Immunity
por: Hastings, Karen Taraszka
Publicado: (2013)

The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers
por: Cloutier, Maryse, et al.
Publicado: (2021)

Isoforms of the invariant chain regulate transport of MHC class II molecules to antigen processing compartments
Publicado: (1996)

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins
por: López de Castro, José A.
Publicado: (2018)

Peptidomes and Structures Illustrate Two Distinguishing Mechanisms of Alternating the Peptide Plasticity Caused by Swine MHC Class I Micropolymorphism
por: Wei, Xiaohui, et al.
Publicado: (2021)

Organizing MHC Class II Presentation
por: Fooksman, David R.
Publicado: (2014)

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain
Publicado: (1986)

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
por: Wieczorek, Marek, et al.
Publicado: (2017)

Targeting the MHC Class II antigen presentation pathway in cancer immunotherapy
por: Thibodeau, Jacques, et al.
Publicado: (2012)

MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity
por: Tsai, Sue, et al.
Publicado: (2013)

MHC Class II Auto-Antigen Presentation is Unconventional
por: Sadegh-Nasseri, Scheherazade, et al.
Publicado: (2015)

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display
por: Wickström, Stina L., et al.
Publicado: (2019)

Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules
Publicado: (1996)

Antigen Processing for MHC Class II Presentation via Autophagy
por: Münz, Christian
Publicado: (2012)

Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination
por: Cho, Kyung-Jin, et al.
Publicado: (2013)

Molecular Determinants Regulating the Plasticity of the MHC Class II Immunopeptidome
por: Santambrogio, Laura
Publicado: (2022)

HLA-DO and Its Role in MHC Class II Antigen Presentation
por: Poluektov, Yuri O., et al.
Publicado: (2013)

A Missing Switch in Peptide Exchange for MHC Class II Molecules
por: Freund, Christian, et al.
Publicado: (2019)

T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1(b) with TAP-Independent Peptides Are Semi-Invariant Lymphocytes
por: Doorduijn, Elien M., et al.
Publicado: (2018)

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis
por: Harrington, Em P, et al.
Publicado: (2023)

Characterization of the Class I MHC Peptidome Resulting From DNCB Exposure of HaCaT Cells
por: Bailey, Alistair, et al.
Publicado: (2020)

Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal
por: Ferrante, Andrea
Publicado: (2013)

Toward a Network Model of MHC Class II-Restricted Antigen Processing
por: Miller, Michael A., et al.
Publicado: (2013)

Structural Comparison Between MHC Classes I and II; in Evolution, a Class-II-Like Molecule Probably Came First
por: Wu, Yanan, et al.
Publicado: (2021)

Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment
Publicado: (1994)

Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines
Publicado: (1994)

Stoichiometry of HLA Class II-Invariant Chain Oligomers
por: Koch, Norbert, et al.
Publicado: (2011)

Streptococcus suis Serotype 2 Infection Impairs Interleukin-12 Production and the MHC-II-Restricted Antigen Presentation Capacity of Dendritic Cells
por: Letendre, Corinne, et al.
Publicado: (2018)

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
por: James, Eddie A., et al.
Publicado: (2009)

Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways
por: Leung, Carol S. K.
Publicado: (2015)

Macroautophagy in Endogenous Processing of Self- and Pathogen-Derived Antigens for MHC Class II Presentation
por: Duraes, Fernanda V., et al.
Publicado: (2015)

The partial dissociation of MHC class I–bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1
por: Papakyriakou, Athanasios, et al.
Publicado: (2018)

Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules
por: Ferrari, Giorgio, et al.
Publicado: (1997)

Enhanced Vaccine-Induced CD8(+) T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class II Invariant Chain
por: Spencer, Alexandra J., et al.
Publicado: (2014)

Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells
por: Avalos, Ana M., et al.
Publicado: (2014)

Epithelial MHC Class II Expression and Its Role in Antigen Presentation in the Gastrointestinal and Respiratory Tracts
por: Wosen, Jonathan E., et al.
Publicado: (2018)

Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA
por: Celesti, Fabrizio, et al.
Publicado: (2023)

The MHC Class-I Transactivator NLRC5: Implications to Cancer Immunology and Potential Applications to Cancer Immunotherapy
por: Shukla, Akhil, et al.
Publicado: (2021)

FMF Is Associated With a Wide Spectrum of MHC Class I- and Allied SpA Disorders but Not With Classical MHC Class II-Associated Autoimmune Disease: Insights From a Large Cohort Study
por: Watad, Abdulla, et al.
Publicado: (2019)

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation
por: Baptista, Antonio P, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kbtsjem2jl2v0985qf59l7rf7n