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Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome

The peptide repertoire (peptidome) associated with MHC class II molecules (MHCIIs) is influenced by the polymorphic nature of the peptide binding groove but also by cell-intrinsic factors. The invariant chain (Ii) chaperones MHCIIs, affecting their folding and trafficking. Recent discoveries relatin...

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Detalles Bibliográficos
Autores principales:	Fortin, Jean-Simon, Cloutier, Maryse, Thibodeau, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861868/ https://www.ncbi.nlm.nih.gov/pubmed/24379812 http://dx.doi.org/10.3389/fimmu.2013.00443

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