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Insights from Zebrafish and Mouse Models on the Activity and Safety of Ar-Turmerone as a Potential Drug Candidate for the Treatment of Epilepsy

In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its sesquiterpenoids (ar-turmerone, α-, β-turmerone and α-atlantone) in both zebrafish and mouse models of chemically-induced seizures using pentylenetetrazole (PTZ). In this follow-up study, we aimed at evaluating t...

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Detalles Bibliográficos
Autores principales: Orellana-Paucar, Adriana Monserrath, Afrikanova, Tatiana, Thomas, Joice, Aibuldinov, Yelaman K., Dehaen, Wim, de Witte, Peter A. M., Esguerra, Camila V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862488/
https://www.ncbi.nlm.nih.gov/pubmed/24349101
http://dx.doi.org/10.1371/journal.pone.0081634