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Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles

The high aqueous solubility, poor permeability, and absorption of berberine (BBR) result in its low plasma level after oral administration, which greatly limits its clinical application. BBR solid lipid nanoparticles (SLNs) were prepared to achieve improved bioavailability and prolonged effect. Deve...

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Detalles Bibliográficos
Autores principales:	Xue, Mei, Yang, Ming-xing, Zhang, Wei, Li, Xiu-min, Gao, De-hong, Ou, Zhi-min, Li, Zhi-peng, Liu, Su-huan, Li, Xue-jun, Yang, Shu-yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862509/ https://www.ncbi.nlm.nih.gov/pubmed/24353417 http://dx.doi.org/10.2147/IJN.S51262

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