Mutation Inactivation of Nijmegen Breakage Syndrome Gene (NBS1) in Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Nijmegen breakage syndrome (NBS) with NBS1 germ-line mutation is a human autosomal recessive disease characterized by genomic instability and enhanced cancer predisposition. The NBS1 gene codes for a protein, Nbs1(p95/Nibrin), involved in the processing/repair of DNA double-strand breaks. Hepatocell...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Hong, Yu, Li, Man, Long, Jiang, Zhao, Yan-Ping, Zhang, Jun-Xia, Li, Qian, You, Hong, Tong, Wei-Min, Jia, Ji-Dong, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862623/
https://www.ncbi.nlm.nih.gov/pubmed/24349281
http://dx.doi.org/10.1371/journal.pone.0082426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862623/
https://www.ncbi.nlm.nih.gov/pubmed/24349281
http://dx.doi.org/10.1371/journal.pone.0082426

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