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Mutation Inactivation of Nijmegen Breakage Syndrome Gene (NBS1) in Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Nijmegen breakage syndrome (NBS) with NBS1 germ-line mutation is a human autosomal recessive disease characterized by genomic instability and enhanced cancer predisposition. The NBS1 gene codes for a protein, Nbs1(p95/Nibrin), involved in the processing/repair of DNA double-strand breaks. Hepatocell...

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Detalles Bibliográficos
Autores principales:	Wang, Yan, Hong, Yu, Li, Man, Long, Jiang, Zhao, Yan-Ping, Zhang, Jun-Xia, Li, Qian, You, Hong, Tong, Wei-Min, Jia, Ji-Dong, Huang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862623/ https://www.ncbi.nlm.nih.gov/pubmed/24349281 http://dx.doi.org/10.1371/journal.pone.0082426

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