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REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer
The levels of regenerating islet-derived 3β (REG3β) in the serum and pancreatic juice of patients affected by pancreatic ductal adenocarcinomas are increased. However, whether such an elevation is relevant to oncogenesis and tumor progression has not yet been carefully examined. We have recently dem...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862636/ https://www.ncbi.nlm.nih.gov/pubmed/24353919 http://dx.doi.org/10.4161/onci.26404 |
| _version_ | 1782295766402859008 |
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| author | Folch-Puy, Emma |
| author_facet | Folch-Puy, Emma |
| author_sort | Folch-Puy, Emma |
| collection | PubMed |
| description | The levels of regenerating islet-derived 3β (REG3β) in the serum and pancreatic juice of patients affected by pancreatic ductal adenocarcinomas are increased. However, whether such an elevation is relevant to oncogenesis and tumor progression has not yet been carefully examined. We have recently demonstrated that silencing REG3β in a pancreatic cancer model impairs tumor growth by skewing macrophage polarization. |
| format | Online Article Text |
| id | pubmed-3862636 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-38626362013-12-18 REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer Folch-Puy, Emma Oncoimmunology Author's View The levels of regenerating islet-derived 3β (REG3β) in the serum and pancreatic juice of patients affected by pancreatic ductal adenocarcinomas are increased. However, whether such an elevation is relevant to oncogenesis and tumor progression has not yet been carefully examined. We have recently demonstrated that silencing REG3β in a pancreatic cancer model impairs tumor growth by skewing macrophage polarization. Landes Bioscience 2013-11-01 2013-10-09 /pmc/articles/PMC3862636/ /pubmed/24353919 http://dx.doi.org/10.4161/onci.26404 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Folch-Puy, Emma REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title | REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title_full | REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title_fullStr | REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title_full_unstemmed | REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title_short | REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| title_sort | reg3β contributes to the immunosuppressive microenvironment of pancreatic cancer |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862636/ https://www.ncbi.nlm.nih.gov/pubmed/24353919 http://dx.doi.org/10.4161/onci.26404 |
| work_keys_str_mv | AT folchpuyemma reg3bcontributestotheimmunosuppressivemicroenvironmentofpancreaticcancer |