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Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis

Vacuolating cytotoxin A (VacA) is one of the important virulence factors produced by H. pylori. VacA induces apoptotic cell death, which is potentiated by ammonia. VacA also causes cell death by mitochondrial damage, via signaling pathways that are not fully defined. Our aim was to determine whether...

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Detalles Bibliográficos
Autores principales: Akazawa, Yuko, Isomoto, Hajime, Matsushima, Kayoko, Kanda, Tsutomu, Minami, Hitomi, Yamaghchi, Naoyuki, Taura, Naota, Shiozawa, Ken, Ohnita, Ken, Takeshima, Fuminao, Nakano, Masayuki, Moss, Joel, Hirayama, Toshiya, Nakao, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862672/
https://www.ncbi.nlm.nih.gov/pubmed/24349255
http://dx.doi.org/10.1371/journal.pone.0082322