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Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis
Vacuolating cytotoxin A (VacA) is one of the important virulence factors produced by H. pylori. VacA induces apoptotic cell death, which is potentiated by ammonia. VacA also causes cell death by mitochondrial damage, via signaling pathways that are not fully defined. Our aim was to determine whether...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862672/ https://www.ncbi.nlm.nih.gov/pubmed/24349255 http://dx.doi.org/10.1371/journal.pone.0082322 |