Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression

We examined the efficacy of using attenuated non-replicating Toxoplasma gondii uracil auxotrophs that can be safely delivered as anticancer immunotherapeutics. This strategy exerted remarkable therapeutic activity in murine models of melanoma and ovarian carcinoma, and holds broad potential for the...

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Detalles Bibliográficos
Autores principales: Fox, Barbara A, Sanders, Kiah L, Bzik, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862683/
https://www.ncbi.nlm.nih.gov/pubmed/24353916
http://dx.doi.org/10.4161/onci.26296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862683/
https://www.ncbi.nlm.nih.gov/pubmed/24353916
http://dx.doi.org/10.4161/onci.26296

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