Monocyte-derived dendritic cells: Emerging players in the antitumor immune response

The elicitation of efficient antitumor immune responses requires the optimal activation of tumor-associated dendritic cells (DCs). Our comparison of the effect of various immunostimulatory treatments on DCs revealed that the best predictor of the success of immunotherapy is not the activation of exi...

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Detalles Bibliográficos
Autores principales: Kuhn, Sabine, Ronchese, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862688/
https://www.ncbi.nlm.nih.gov/pubmed/24353920
http://dx.doi.org/10.4161/onci.26443
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author Kuhn, Sabine
Ronchese, Franca
author_facet Kuhn, Sabine
Ronchese, Franca
author_sort Kuhn, Sabine
collection PubMed
description The elicitation of efficient antitumor immune responses requires the optimal activation of tumor-associated dendritic cells (DCs). Our comparison of the effect of various immunostimulatory treatments on DCs revealed that the best predictor of the success of immunotherapy is not the activation of existing DC populations, but the appearance of a population of monocyte-derived DC in tumor-draining lymph nodes.
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spelling pubmed-38626882013-12-18 Monocyte-derived dendritic cells: Emerging players in the antitumor immune response Kuhn, Sabine Ronchese, Franca Oncoimmunology Author's View The elicitation of efficient antitumor immune responses requires the optimal activation of tumor-associated dendritic cells (DCs). Our comparison of the effect of various immunostimulatory treatments on DCs revealed that the best predictor of the success of immunotherapy is not the activation of existing DC populations, but the appearance of a population of monocyte-derived DC in tumor-draining lymph nodes. Landes Bioscience 2013-11-01 2013-10-09 /pmc/articles/PMC3862688/ /pubmed/24353920 http://dx.doi.org/10.4161/onci.26443 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Kuhn, Sabine
Ronchese, Franca
Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title_full Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title_fullStr Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title_full_unstemmed Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title_short Monocyte-derived dendritic cells: Emerging players in the antitumor immune response
title_sort monocyte-derived dendritic cells: emerging players in the antitumor immune response
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862688/
https://www.ncbi.nlm.nih.gov/pubmed/24353920
http://dx.doi.org/10.4161/onci.26443
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