Mitochondrial DNA Damage via Augmented Oxidative Stress Regulates Endoplasmic Reticulum Stress and Autophagy: Crosstalk, Links and Signaling

Saturated free fatty acids (FFAs) have been implicated in the increase of oxidative stress, mitochondrial dysfunction, endoplasmic reticulum (ER) stress, autophagy, and insulin resistance (IR) observed in skeletal muscle. Previously, we have shown that palmitate-induced mitochondrial DNA (mtDNA) dam...

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Detalles Bibliográficos
Autores principales: Yuzefovych, Larysa V., LeDoux, Susan P., Wilson, Glenn L., Rachek, Lyudmila I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862720/
https://www.ncbi.nlm.nih.gov/pubmed/24349491
http://dx.doi.org/10.1371/journal.pone.0083349

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