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Rab39a Interacts with Phosphatidylinositol 3-Kinase and Negatively Regulates Autophagy Induced by Lipopolysaccharide Stimulation in Macrophages

Rab39a has pleiotropic functions in phagosome maturation, inflammatory activation and neuritogenesis. Here, we characterized Rab39a function in membrane trafficking of phagocytosis and autophagy induction in macrophages. Rab39a localized to the periphery of LAMP2-positive vesicles and showed the sim...

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Detalles Bibliográficos
Autores principales: Seto, Shintaro, Sugaya, Keiko, Tsujimura, Kunio, Nagata, Toshi, Horii, Toshinobu, Koide, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862771/
https://www.ncbi.nlm.nih.gov/pubmed/24349490
http://dx.doi.org/10.1371/journal.pone.0083324