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Rab39a Interacts with Phosphatidylinositol 3-Kinase and Negatively Regulates Autophagy Induced by Lipopolysaccharide Stimulation in Macrophages
Rab39a has pleiotropic functions in phagosome maturation, inflammatory activation and neuritogenesis. Here, we characterized Rab39a function in membrane trafficking of phagocytosis and autophagy induction in macrophages. Rab39a localized to the periphery of LAMP2-positive vesicles and showed the sim...
Autores principales: | Seto, Shintaro, Sugaya, Keiko, Tsujimura, Kunio, Nagata, Toshi, Horii, Toshinobu, Koide, Yukio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862771/ https://www.ncbi.nlm.nih.gov/pubmed/24349490 http://dx.doi.org/10.1371/journal.pone.0083324 |
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