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Mannitol Enhances Antibiotic Sensitivity of Persister Bacteria in Pseudomonas aeruginosa Biofilms

The failure of antibiotic therapies to clear Pseudomonas aeruginosa lung infection, the key mortality factor for cystic fibrosis (CF) patients, is partly attributed to the high tolerance of P. aeruginosa biofilms. Mannitol has previously been found to restore aminoglycoside sensitivity in Escherichi...

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Detalles Bibliográficos
Autores principales: Barraud, Nicolas, Buson, Alberto, Jarolimek, Wolfgang, Rice, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862834/
https://www.ncbi.nlm.nih.gov/pubmed/24349568
http://dx.doi.org/10.1371/journal.pone.0084220

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