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The Effect of Apigenin on Pharmacokinetics of Imatinib and Its Metabolite N-Desmethyl Imatinib in Rats

The purpose of this study was to determine the effect of apigenin on the pharmacokinetics of imatinib and N-desmethyl imatinib in rats. Healthy male SD rats were randomly divided into four groups: A group (the control group), B group (the long-term administration of 165 mg/kg apigenin for 15 days),...

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Detalles Bibliográficos
Autores principales:	Liu, Xian-yun, Xu, Tao, Li, Wan-shu, Luo, Jun, Geng, Pei-wu, Wang, Li, Xia, Meng-ming, Chen, Meng-chun, Yu, Lei, Hu, Guo-xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863468/ https://www.ncbi.nlm.nih.gov/pubmed/24369535 http://dx.doi.org/10.1155/2013/789184

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