Human Mesenchymal Stem Cells Provide Protection against Radiation-Induced Liver Injury by Antioxidative Process, Vasculature Protection, Hepatocyte Differentiation, and Trophic Effects

To evaluate the potential therapeutic effect of the infusion of hMSCs for the correction of liver injuries, we performed total body radiation exposure of NOD/SCID mice. After irradiation, mir-27b level decreases in liver, increasing the directional migration of hMSCs by upregulating SDF1α. A signifi...

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Detalles Bibliográficos
Autores principales: Francois, Sabine, Mouiseddine, Moubarak, Allenet-Lepage, Bénédicte, Voswinkel, Jan, Douay, Luc, Benderitter, Marc, Chapel, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863471/
https://www.ncbi.nlm.nih.gov/pubmed/24369528
http://dx.doi.org/10.1155/2013/151679

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