Low-Cytotoxic Synthetic Bromorutaecarpine Exhibits Anti-Inflammation and Activation of Transient Receptor Potential Vanilloid Type 1 Activities

Rutaecarpine (RUT), the major bioactive ingredient isolated from the Chinese herb Evodia rutaecarpa, possesses a wide spectrum of biological activities, including anti-inflammation and preventing cardiovascular diseases. However, its high cytotoxicity hampers pharmaceutical development. We designed...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Ming, Gu, Jiun-An, Rau, Tin-Gan, Yang, Che-Hsiung, Yang, Wei-Chi, Huang, Shih-Hao, Lin, Feng-Yen, Lin, Chun-Mao, Huang, Sheng-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863474/
https://www.ncbi.nlm.nih.gov/pubmed/24369537
http://dx.doi.org/10.1155/2013/795095

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