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Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI
Motor imagery training is an effective approach for motor skill learning and motor function rehabilitation. As a novel method of motor imagery training, real-time fMRI (rtfMRI) enables individuals to acquire self-control of localized brain activation, achieving desired changes in behavior. The regul...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863758/ https://www.ncbi.nlm.nih.gov/pubmed/24379775 http://dx.doi.org/10.3389/fnhum.2013.00866 |
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author | Zhao, Xiaojie Zhang, Hang Song, Sutao Ye, Qing Guo, Jia Yao, Li |
author_facet | Zhao, Xiaojie Zhang, Hang Song, Sutao Ye, Qing Guo, Jia Yao, Li |
author_sort | Zhao, Xiaojie |
collection | PubMed |
description | Motor imagery training is an effective approach for motor skill learning and motor function rehabilitation. As a novel method of motor imagery training, real-time fMRI (rtfMRI) enables individuals to acquire self-control of localized brain activation, achieving desired changes in behavior. The regulation of target region activation by rtfMRI often alters the activation of related brain regions. However, the interaction between the target region and these related regions is unclear. The Granger causality model (GCM) is a data-driven method that can explore the causal interaction between brain regions. In this study, we employed rtfMRI to train subjects to regulate the activation of the ipsilateral dorsal premotor area (dPMA) during motor imagery training, and we calculated the causal interaction of the dPMA with other motor-related regions based on the GCM. The results demonstrated that as the activity of the dPMA changed during rtfMRI training, the interaction of the target region with other related regions became significantly altered, and behavioral performance was improved after training. The altered interaction primarily exhibited as an increased unidirectional interaction from the dPMA to the other regions. These findings support the dominant role of the dPMA in motor skill learning via rtfMRI training and may indicate how activation of the target region interacts with the activation of other related regions. |
format | Online Article Text |
id | pubmed-3863758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-38637582013-12-30 Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI Zhao, Xiaojie Zhang, Hang Song, Sutao Ye, Qing Guo, Jia Yao, Li Front Hum Neurosci Neuroscience Motor imagery training is an effective approach for motor skill learning and motor function rehabilitation. As a novel method of motor imagery training, real-time fMRI (rtfMRI) enables individuals to acquire self-control of localized brain activation, achieving desired changes in behavior. The regulation of target region activation by rtfMRI often alters the activation of related brain regions. However, the interaction between the target region and these related regions is unclear. The Granger causality model (GCM) is a data-driven method that can explore the causal interaction between brain regions. In this study, we employed rtfMRI to train subjects to regulate the activation of the ipsilateral dorsal premotor area (dPMA) during motor imagery training, and we calculated the causal interaction of the dPMA with other motor-related regions based on the GCM. The results demonstrated that as the activity of the dPMA changed during rtfMRI training, the interaction of the target region with other related regions became significantly altered, and behavioral performance was improved after training. The altered interaction primarily exhibited as an increased unidirectional interaction from the dPMA to the other regions. These findings support the dominant role of the dPMA in motor skill learning via rtfMRI training and may indicate how activation of the target region interacts with the activation of other related regions. Frontiers Media S.A. 2013-12-16 /pmc/articles/PMC3863758/ /pubmed/24379775 http://dx.doi.org/10.3389/fnhum.2013.00866 Text en Copyright © 2013 Zhao, Zhang, Song, Ye, Guo and Yao. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Zhao, Xiaojie Zhang, Hang Song, Sutao Ye, Qing Guo, Jia Yao, Li Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title | Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title_full | Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title_fullStr | Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title_full_unstemmed | Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title_short | Causal interaction following the alteration of target region activation during motor imagery training using real-time fMRI |
title_sort | causal interaction following the alteration of target region activation during motor imagery training using real-time fmri |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863758/ https://www.ncbi.nlm.nih.gov/pubmed/24379775 http://dx.doi.org/10.3389/fnhum.2013.00866 |
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