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Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension()
Nitric oxide (NO)-derived metabolites including the anion nitrite can recycle back to NO and thus complement NO formation independent of NO synthases. While nitrite is as a major vascular storage pool and source of NO, little is known about drugs that increase tissue nitrite concentrations. This stu...
Autores principales: | Guimarães, Danielle A., Rizzi, Elen, Ceron, Carla S., Pinheiro, Lucas C., Gerlach, Raquel F., Tanus-Santos, Jose E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863772/ https://www.ncbi.nlm.nih.gov/pubmed/24363994 http://dx.doi.org/10.1016/j.redox.2013.11.004 |
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