Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly

The strongest risk factor for developing Alzheimer's Disease (AD) is age. Here, we study the relationship between ageing and AD using a systems biology approach that employs a Drosophila (fruitfly) model of AD in which the flies overexpress the human Aβ(42) peptide. We identified 712 genes that...

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Detalles Bibliográficos
Autores principales: Favrin, G., Bean, D. M., Bilsland, E., Boyer, H., Fischer, B. E., Russell, S., Crowther, D. C., Baylis, H. A., Oliver, S. G., Giannakou, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863820/
https://www.ncbi.nlm.nih.gov/pubmed/24336499
http://dx.doi.org/10.1038/srep03512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863820/
https://www.ncbi.nlm.nih.gov/pubmed/24336499
http://dx.doi.org/10.1038/srep03512

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