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Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model

BACKGROUND: Human regulatory T cells (Treg) offer an attractive adjunctive therapy to reduce current reliance on lifelong, nonspecific immunosuppression after transplantation. Here, we evaluated the ability of ex vivo expanded human Treg to prevent the rejection of islets of Langerhans in a humanize...

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Detalles Bibliográficos
Autores principales:	Wu, Douglas C., Hester, Joanna, Nadig, Satish N., Zhang, Wei, Trzonkowski, Piotr, Gray, Derek, Hughes, Stephen, Johnson, Paul, Wood, Kathryn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2013
Materias:	Basic and Experimental Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864182/ https://www.ncbi.nlm.nih.gov/pubmed/23917725 http://dx.doi.org/10.1097/TP.0b013e31829fa271

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