Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update

The structure and function of the heart needs to be understood in three dimensions. We give a brief historical summary of the methods by which such an understanding has been sought, and some practical details of the relatively new technique of micro-CT with iodine contrast enhancement in samples fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Jarvis, Jonathan C., Stephenson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864221/
https://www.ncbi.nlm.nih.gov/pubmed/24400272
http://dx.doi.org/10.3389/fped.2013.00026
_version_ 1782295910573670400
author Jarvis, Jonathan C.
Stephenson, Robert
author_facet Jarvis, Jonathan C.
Stephenson, Robert
author_sort Jarvis, Jonathan C.
collection PubMed
description The structure and function of the heart needs to be understood in three dimensions. We give a brief historical summary of the methods by which such an understanding has been sought, and some practical details of the relatively new technique of micro-CT with iodine contrast enhancement in samples from rat and rabbit. We discuss how the improved anatomical detail available in fixed cadaveric hearts will enhance our ability to model and to understand the integrated function of the cardiomyocytes, conducting tissues, and fibrous supporting structures that generate the pumping function of the heart.
format Online
Article
Text
id pubmed-3864221
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-38642212014-01-07 Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update Jarvis, Jonathan C. Stephenson, Robert Front Pediatr Pediatrics The structure and function of the heart needs to be understood in three dimensions. We give a brief historical summary of the methods by which such an understanding has been sought, and some practical details of the relatively new technique of micro-CT with iodine contrast enhancement in samples from rat and rabbit. We discuss how the improved anatomical detail available in fixed cadaveric hearts will enhance our ability to model and to understand the integrated function of the cardiomyocytes, conducting tissues, and fibrous supporting structures that generate the pumping function of the heart. Frontiers Media S.A. 2013-10-10 /pmc/articles/PMC3864221/ /pubmed/24400272 http://dx.doi.org/10.3389/fped.2013.00026 Text en Copyright © 2013 Jarvis and Stephenson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Jarvis, Jonathan C.
Stephenson, Robert
Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title_full Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title_fullStr Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title_full_unstemmed Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title_short Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
title_sort studying the microanatomy of the heart in three dimensions: a practical update
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864221/
https://www.ncbi.nlm.nih.gov/pubmed/24400272
http://dx.doi.org/10.3389/fped.2013.00026
work_keys_str_mv AT jarvisjonathanc studyingthemicroanatomyoftheheartinthreedimensionsapracticalupdate
AT stephensonrobert studyingthemicroanatomyoftheheartinthreedimensionsapracticalupdate

Ejemplares similares