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Efficient Gene Silencing by Self-Assembled Complexes of siRNA and Symmetrical Fatty Acid Amides of Spermine

Gene silencing by siRNA (synthetic dsRNA of 21-25 nucleotides) is a well established biological tool in gene expression studies and has a promising therapeutic potential for difficult-to-treat diseases. Five fatty acids of various chain length and oxidation state (C12:0, C18:0, C18:1, C18:2, C22:1)...

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Detalles Bibliográficos
Autores principales:	Metwally, Abdelkader A., Pourzand, Charareh, Blagbrough, Ian S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864230/ https://www.ncbi.nlm.nih.gov/pubmed/24310492 http://dx.doi.org/10.3390/pharmaceutics3020125

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