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Cryptococcus neoformans Ex Vivo Capsule Size Is Associated With Intracranial Pressure and Host Immune Response in HIV-associated Cryptococcal Meningitis

Background. The Cryptococcus neoformans polysaccharide capsule is a well-characterized virulence factor with immunomodulatory properties. The organism and/or shed capsule is postulated to raise intracranial pressure (ICP) in cryptococcal meningitis (CM) by mechanical obstruction of cerebrospinal flu...

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Detalles Bibliográficos
Autores principales:	Robertson, Emma J., Najjuka, Grace, Rolfes, Melissa A., Akampurira, Andrew, Jain, Neena, Anantharanjit, Janani, von Hohenberg, Maximilian, Tassieri, Manlio, Carlsson, Allan, Meya, David B., Harrison, Thomas S., Fries, Bettina C., Boulware, David R., Bicanic, Tihana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864387/ https://www.ncbi.nlm.nih.gov/pubmed/23945372 http://dx.doi.org/10.1093/infdis/jit435

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