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Mutants of phage bIL67 RuvC with enhanced Holliday junction binding selectivity and resolution symmetry

Viral and bacterial Holliday junction resolvases differ in specificity with the former typically being more promiscuous, acting on a variety of branched DNA substrates, while the latter exclusively targets Holliday junctions. We have determined the crystal structure of a RuvC resolvase from bacterio...

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Detalles Bibliográficos
Autores principales:	Green, Victoria, Curtis, Fiona A, Sedelnikova, Svetlana, Rafferty, John B, Sharples, Gary J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864405/ https://www.ncbi.nlm.nih.gov/pubmed/23888987 http://dx.doi.org/10.1111/mmi.12343

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