Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery

Bone graft substitutes have been used routinely for spine fusion for decades, yet clinical evidence establishing comparative data remains sparse. With recent scrutiny paid to the outcomes, complications, and costs associated with osteobiologics, a need to improve available data guiding efficacious u...

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Autores principales: Hsu, Wellington K., Nickoli, M. S., Wang, J. C., Lieberman, J. R., An, H. S., Yoon, S. T., Youssef, J. A., Brodke, D. S., McCullough, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864464/
https://www.ncbi.nlm.nih.gov/pubmed/24353975
http://dx.doi.org/10.1055/s-0032-1315454
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author Hsu, Wellington K.
Nickoli, M. S.
Wang, J. C.
Lieberman, J. R.
An, H. S.
Yoon, S. T.
Youssef, J. A.
Brodke, D. S.
McCullough, C. M.
author_facet Hsu, Wellington K.
Nickoli, M. S.
Wang, J. C.
Lieberman, J. R.
An, H. S.
Yoon, S. T.
Youssef, J. A.
Brodke, D. S.
McCullough, C. M.
author_sort Hsu, Wellington K.
collection PubMed
description Bone graft substitutes have been used routinely for spine fusion for decades, yet clinical evidence establishing comparative data remains sparse. With recent scrutiny paid to the outcomes, complications, and costs associated with osteobiologics, a need to improve available data guiding efficacious use exists. We review the currently available clinical literature, studying the outcomes of various biologics in posterolateral lumbar spine fusion, and establish the need for a multicenter, independent osteobiologics registry.
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spelling pubmed-38644642013-12-18 Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery Hsu, Wellington K. Nickoli, M. S. Wang, J. C. Lieberman, J. R. An, H. S. Yoon, S. T. Youssef, J. A. Brodke, D. S. McCullough, C. M. Global Spine J Article Bone graft substitutes have been used routinely for spine fusion for decades, yet clinical evidence establishing comparative data remains sparse. With recent scrutiny paid to the outcomes, complications, and costs associated with osteobiologics, a need to improve available data guiding efficacious use exists. We review the currently available clinical literature, studying the outcomes of various biologics in posterolateral lumbar spine fusion, and establish the need for a multicenter, independent osteobiologics registry. Georg Thieme Verlag KG 2012-10-09 2012-12 /pmc/articles/PMC3864464/ /pubmed/24353975 http://dx.doi.org/10.1055/s-0032-1315454 Text en © Thieme Medical Publishers
spellingShingle Article
Hsu, Wellington K.
Nickoli, M. S.
Wang, J. C.
Lieberman, J. R.
An, H. S.
Yoon, S. T.
Youssef, J. A.
Brodke, D. S.
McCullough, C. M.
Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title_full Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title_fullStr Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title_full_unstemmed Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title_short Improving the Clinical Evidence of Bone Graft Substitute Technology in Lumbar Spine Surgery
title_sort improving the clinical evidence of bone graft substitute technology in lumbar spine surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864464/
https://www.ncbi.nlm.nih.gov/pubmed/24353975
http://dx.doi.org/10.1055/s-0032-1315454
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