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A Conserved Sequence Extending Motif III of the Motor Domain in the Snf2-Family DNA Translocase Rad54 Is Critical for ATPase Activity

Rad54 is a dsDNA-dependent ATPase that translocates on duplex DNA. Its ATPase function is essential for homologous recombination, a pathway critical for meiotic chromosome segregation, repair of complex DNA damage, and recovery of stalled or broken replication forks. In recombination, Rad54 cooperat...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Ping, Janke, Ryan, Kingsley, James, Luo, Jerry, Fasching, Clare, Ehmsen, Kirk T., Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864901/
https://www.ncbi.nlm.nih.gov/pubmed/24358152
http://dx.doi.org/10.1371/journal.pone.0082184

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