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Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab

Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochem...

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Detalles Bibliográficos
Autor principal: Sorscher, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864990/
https://www.ncbi.nlm.nih.gov/pubmed/24376362
http://dx.doi.org/10.2147/CMAR.S55091
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author Sorscher, Steven
author_facet Sorscher, Steven
author_sort Sorscher, Steven
collection PubMed
description Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone.
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spelling pubmed-38649902013-12-27 Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab Sorscher, Steven Cancer Manag Res Case Report Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone. Dove Medical Press 2013-12-11 /pmc/articles/PMC3864990/ /pubmed/24376362 http://dx.doi.org/10.2147/CMAR.S55091 Text en © 2014 Sorscher. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Sorscher, Steven
Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title_full Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title_fullStr Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title_full_unstemmed Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title_short Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
title_sort marked radiographic response of a her-2-overexpressing biliary cancer to trastuzumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864990/
https://www.ncbi.nlm.nih.gov/pubmed/24376362
http://dx.doi.org/10.2147/CMAR.S55091
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