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Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochem...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864990/ https://www.ncbi.nlm.nih.gov/pubmed/24376362 http://dx.doi.org/10.2147/CMAR.S55091 |
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author | Sorscher, Steven |
author_facet | Sorscher, Steven |
author_sort | Sorscher, Steven |
collection | PubMed |
description | Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone. |
format | Online Article Text |
id | pubmed-3864990 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-38649902013-12-27 Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab Sorscher, Steven Cancer Manag Res Case Report Trastuzumab is a monoclonal antibody targeting HER-2. HER-2 overexpression has been described in gallbladder cancer and in cholangiocarcinoma. This report describes the first case of a patient with HER-2 overexpressing metastatic gallbladder adenocarcinoma and responding radiographically and biochemically to trastuzumab alone. Dove Medical Press 2013-12-11 /pmc/articles/PMC3864990/ /pubmed/24376362 http://dx.doi.org/10.2147/CMAR.S55091 Text en © 2014 Sorscher. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Report Sorscher, Steven Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title | Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title_full | Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title_fullStr | Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title_full_unstemmed | Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title_short | Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab |
title_sort | marked radiographic response of a her-2-overexpressing biliary cancer to trastuzumab |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864990/ https://www.ncbi.nlm.nih.gov/pubmed/24376362 http://dx.doi.org/10.2147/CMAR.S55091 |
work_keys_str_mv | AT sorschersteven markedradiographicresponseofaher2overexpressingbiliarycancertotrastuzumab |