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Mdm20 Stimulates PolyQ Aggregation via Inhibiting Autophagy Through Akt-Ser473 Phosphorylation

Mdm20 is an auxiliary subunit of the NatB complex, which includes Nat5, the catalytic subunit for protein N-terminal acetylation. The NatB complex catalyzes N-acetylation during de novo protein synthesis initiation; however, recent evidence from yeast suggests that NatB also affects post-translation...

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Detalles Bibliográficos
Autores principales: Yasuda, Kunihiko, Ohyama, Kyoji, Onga, Kazuko, Kakizuka, Akira, Mori, Nozomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865000/
https://www.ncbi.nlm.nih.gov/pubmed/24358196
http://dx.doi.org/10.1371/journal.pone.0082523