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Mdm20 Stimulates PolyQ Aggregation via Inhibiting Autophagy Through Akt-Ser473 Phosphorylation
Mdm20 is an auxiliary subunit of the NatB complex, which includes Nat5, the catalytic subunit for protein N-terminal acetylation. The NatB complex catalyzes N-acetylation during de novo protein synthesis initiation; however, recent evidence from yeast suggests that NatB also affects post-translation...
Autores principales: | Yasuda, Kunihiko, Ohyama, Kyoji, Onga, Kazuko, Kakizuka, Akira, Mori, Nozomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865000/ https://www.ncbi.nlm.nih.gov/pubmed/24358196 http://dx.doi.org/10.1371/journal.pone.0082523 |
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