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The p27–Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells
Glucocorticoid therapy is an important treatment modality of hematological malignancies, especially T-cell acute lymphoblastic leukemia (T-ALL). Glucocorticoids are known to induce a cell cycle arrest and apoptosis in T-lymphoma cells. We could demonstrate that the cell cycle arrest induced by the s...
Autores principales: | Kullmann, Michael K, Grubbauer, Claudia, Goetsch, Katrin, Jäkel, Heidelinde, Podmirseg, Silvio R, Trockenbacher, Alexander, Ploner, Christian, Cato, Andrew C.B., Weiss, Carsten, Kofler, Reinhard, Hengst, Ludger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865052/ https://www.ncbi.nlm.nih.gov/pubmed/23907123 http://dx.doi.org/10.4161/cc.25622 |
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