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Structural mechanism of ligand activation in human GABA(B) receptor

Human GABA(B) receptor is a G-protein coupled receptor central to inhibitory neurotransmission in the brain. It functions as an obligatory heterodimer of GBR1 and GBR2 subunits. Here we present the first crystal structures of a heterodimeric complex between the extracellular domains of GBR1 and GBR2...

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Detalles Bibliográficos
Autores principales:	Geng, Yong, Bush, Martin, Mosyak, Lidia, Wang, Feng, Fan, Qing R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865065/ https://www.ncbi.nlm.nih.gov/pubmed/24305054 http://dx.doi.org/10.1038/nature12725

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