Cargando…

B Cell Responses to HIV Antigen Are a Potent Correlate of Viremia in HIV-1 Infection and Improve with PD-1 Blockade

Infection with Human Immunodeficiency Virus Type 1 (HIV-1) induces defects of both cellular and humoral immune responses. Impaired CD4+ T cell help and B cell dysfunction may partially explain the low frequency of broadly neutralizing antibodies in HIV-infected individuals. To understand the extent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nicholas, Katherine J., Zern, Emily K., Barnett, Louise, Smith, Rita M., Lorey, Shelly L., Copeland, Courtney A., Sadagopal, Shanmugalakshmi, Kalams, Spyros A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865293/ https://www.ncbi.nlm.nih.gov/pubmed/24358343 http://dx.doi.org/10.1371/journal.pone.0084185

Ejemplares similares

PD-L1 Blockade Differentially Impacts Regulatory T Cells from HIV-Infected Individuals Depending on Plasma Viremia
por: Peligero, Cristina, et al.
Publicado: (2015)

HIV-1 persistent viremia is frequently followed by episodes of low-level viremia
por: Widera, Marek, et al.
Publicado: (2017)

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade
por: Freeman, Gordon J., et al.
Publicado: (2006)

Residual Viremia Is Preceding Viral Blips and Persistent Low-Level Viremia in Treated HIV-1 Patients
por: Hofstra, Laura Marije, et al.
Publicado: (2014)

Reducing the Activity and Secretion of Microbial Antioxidants Enhances the Immunogenicity of BCG
por: Sadagopal, Shanmugalakshmi, et al.
Publicado: (2009)

PD-1 Blockade in Advanced Melanoma in Patients with Hepatitis C and/or HIV
por: Davar, Diwakar, et al.
Publicado: (2015)

Supervised Treatment Interruptions Fail to Control HIV-1 Viremia
Publicado: (2004)

Persistent HIV-1 Viremia on Antiretroviral Therapy: Measurement and Mechanisms
por: Jacobs, Jana L., et al.
Publicado: (2019)

Viral and Host Mediators of Non-Suppressible HIV-1 Viremia
por: Mohammadi, Abbas, et al.
Publicado: (2023)

Residual Viremia in Treated HIV(+) Individuals
por: Conway, Jessica M., et al.
Publicado: (2016)

Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1
por: Mikell, Iliyana, et al.
Publicado: (2011)

HIV Viremia Is Associated With APOL1 Variants and Reduced JC-Viruria
por: Kruzel-Davila, Etty, et al.
Publicado: (2021)

Nonsuppressible viremia during HIV-1 therapy meets molecular virology
por: Emery, Ann, et al.
Publicado: (2023)

Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1
por: Mikell, Iliyana, et al.
Publicado: (2011)

PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads
por: Seung, Edward, et al.
Publicado: (2013)

HIV-1-Specific CAR-T Cells With Cell-Intrinsic PD-1 Checkpoint Blockade Enhance Anti-HIV Efficacy in vivo
por: Jiang, Zhengtao, et al.
Publicado: (2021)

2509: Estimation of HIV viral load using quantitative measurement of HIV-p24 on lateral flow immunoassays
por: Conrad, Joseph A., et al.
Publicado: (2018)

Immunological and virological characterization of HIV-1 viremia controllers in the North Region of Brazil
por: Gomes, Samara Tatielle M., et al.
Publicado: (2017)

Automated Multireplicate Quantification of Persistent HIV-1 Viremia in Individuals on Antiretroviral Therapy
por: Jacobs, Jana L., et al.
Publicado: (2020)

Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
por: Borgognone, Alessandra, et al.
Publicado: (2022)

Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes
por: Yang, Otto O., et al.
Publicado: (2003)

Viremia Trajectories of HIV in HIV-Positive Women in the United States, 1994-2017
por: Kassaye, Seble G., et al.
Publicado: (2019)

Transient Erythema Elevatum Diutinum Associated With HIV Viremia
por: Rashdan, Hannah, et al.
Publicado: (2023)

Impact of Chemotherapy for HIV-1 Related Lymphoma on Residual Viremia and Cellular HIV-1 DNA in Patients on Suppressive Antiretroviral Therapy
por: Cillo, Anthony R., et al.
Publicado: (2014)

Adaptation to HLA-associated immune pressure over the course of HIV infection and in circulating HIV-1 strains
por: Alves, Eric, et al.
Publicado: (2022)

Impact of Raltegravir on immune reconstitution and thymopoiesis in HIV-1-infected patients with undetectable viremia
por: Garrido, C, et al.
Publicado: (2010)

Novel pH sensing semiconductor for point-of-care detection of HIV-1 viremia
por: Gurrala, R., et al.
Publicado: (2016)

A5 Peripheral blood cells contribute to HIV-1 viremia induced by romidepsin
por: Winckelmann, A., et al.
Publicado: (2017)

Impact of maternal HIV-1 viremia on lymphocyte subsets among HIV-exposed uninfected infants: protective mechanism or immunodeficiency
por: Kakkar, Fatima, et al.
Publicado: (2014)

Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes
por: Kochupurakkal, Nora M., et al.
Publicado: (2014)

Leukocyte Telomere Length in HIV-Infected and HIV-Exposed Uninfected Children: Shorter Telomeres with Uncontrolled HIV Viremia
por: Côté, Hélène C. F., et al.
Publicado: (2012)

HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL
por: Kelesidis, Theodoros, et al.
Publicado: (2011)

Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation
por: Swaminathan, Sanjay, et al.
Publicado: (2016)

Plasma Level of Soluble ST2 in Chronically Infected HIV-1 Patients with Suppressed Viremia
por: Younas, Mehwish, et al.
Publicado: (2017)

The dual-target approach in viral HIV-1 viremia testing: An added value to virological monitoring?
por: Amendola, Alessandra, et al.
Publicado: (2020)

Suppression of HIV-Specific and Allogeneic T Cell Activation by Human Regulatory T Cells Is Dependent on the Strength of Signals
por: Antons, Amanda K., et al.
Publicado: (2008)

Increased Prevalence of Liver Fibrosis and HIV Viremia among Patients with HIV, HBV, and Tuberculosis in Botswana
por: Phinius, Bonolo B., et al.
Publicado: (2020)

An update on immunotherapy with PD-1 and PD-L1 blockade
por: Koh, Sung Ae
Publicado: (2021)

Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV
por: Currenti, Jennifer, et al.
Publicado: (2019)

HIV-1 Viremia Prevents the Establishment of Interleukin 2–producing HIV-specific Memory CD4(+) T Cells Endowed with Proliferative Capacity
por: Younes, Souheil-Antoine, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_7ddf0du2l384ou83ola27c6grf