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The Repertoires of Peptides Presented by MHC-II in the Thymus and in Peripheral Tissue: A Clue for Autoimmunity?

T-cell tolerance to self-antigens is established in the thymus through the recognition by developing thymocytes of self-peptide-MHC complexes and induced and maintained in the periphery. Efficient negative selection of auto-reactive T cells in the thymus is dependent on the in situ expression of bot...

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Detalles Bibliográficos
Autores principales:	Collado, Javier A., Guitart, Carolina, Ciudad, M. Teresa, Alvarez, Iñaki, Jaraquemada, Dolores
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865459/ https://www.ncbi.nlm.nih.gov/pubmed/24381570 http://dx.doi.org/10.3389/fimmu.2013.00442

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