A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their development. We show that human ILC2s express skin homing receptors and infiltrate the skin after allergen challenge, where they produce the type 2 cytokines IL-5 and IL-13. Skin-derived ILC2s express the IL-33 rece...

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Detalles Bibliográficos
Autores principales: Salimi, Maryam, Barlow, Jillian L., Saunders, Sean P., Xue, Luzheng, Gutowska-Owsiak, Danuta, Wang, Xinwen, Huang, Li-Chieh, Johnson, David, Scanlon, Seth T., McKenzie, Andrew N.J., Fallon, Padraic G., Ogg, Graham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865470/
https://www.ncbi.nlm.nih.gov/pubmed/24323357
http://dx.doi.org/10.1084/jem.20130351

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