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KIT oncogene inhibition drives intratumoral macrophage M2 polarization

Tumor-associated macrophages (TAMs) are a major component of the cancer microenvironment. Modulation of TAMs is under intense investigation because they are thought to be nearly always of the M2 subtype, which supports tumor growth. Gastrointestinal stromal tumor (GIST) is the most common human sarc...

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Detalles Bibliográficos
Autores principales:	Cavnar, Michael J., Zeng, Shan, Kim, Teresa S., Sorenson, Eric C., Ocuin, Lee M., Balachandran, Vinod P., Seifert, Adrian M., Greer, Jonathan B., Popow, Rachel, Crawley, Megan H., Cohen, Noah A., Green, Benjamin L., Rossi, Ferdinand, Besmer, Peter, Antonescu, Cristina R., DeMatteo, Ronald P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865475/ https://www.ncbi.nlm.nih.gov/pubmed/24323358 http://dx.doi.org/10.1084/jem.20130875

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