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Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons
Disruption of the Frizzled3 (Fz3) gene leads to defects in axonal growth in the VII(th) and XII(th) cranial motor nerves, the phrenic nerve, and the dorsal motor nerve in fore- and hindlimbs. In Fz3(−/−) limbs, dorsal axons stall at a precise location in the nerve plexus, and, in contrast to the phe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865743/ https://www.ncbi.nlm.nih.gov/pubmed/24347548 http://dx.doi.org/10.7554/eLife.01482 |